it is an 64 bit installation, but with all the 32 bit items. the bin32 and the bin64 path is in the path-variable. i also do that:

C:\Ruby24-x64\bin>irb
irb(main):001:0> require 'sqlanywhere'
=> true
irb(main):002:0> api = SQLAnywhere::SQLAnywhereInterface.new()
=> #<sqlanywhere::sqlanywhereinterface:0x00000002dc90b8>
irb(main):003:0> SQLAnywhere::API.sqlany_initialize_interface( api )
=> 0
irb(main):004:0> api.sqlany_init()
(irb):4: [BUG] Segmentation fault
ruby 2.4.1p111 (2017-03-22 revision 58053) [x64-mingw32]

-- Control frame information -----------------------------------------------
c:0020 p:---- s:0099 e:000098 CFUNC  :sqlany_init
c:0019 p:0007 s:0095 e:000094 EVAL   (irb):4 [FINISH]
c:0018 p:---- s:0092 e:000091 CFUNC  :eval
c:0017 p:0025 s:0084 e:000083 METHOD C:/Ruby24-x64/lib/ruby/2.4.0/irb/workspace.rb:87
c:0016 p:0027 s:0076 e:000074 METHOD C:/Ruby24-x64/lib/ruby/2.4.0/irb/context.rb:381
...

[NOTE]
You may have encountered a bug in the Ruby interpreter or extension libraries.
Bug reports are welcome.
For details: http://www.ruby-lang.org/bugreport.html


This application has requested the Runtime to terminate it in an unusual way.
Please contact the application's support team for more information.

C:\Ruby24-x64\bin>

Any Idea???

Thanks, Pascal

As Vlad has asked: Are the mentioned DLLs like dbcapi.dll in the according %SQLANY17%\bin64 subdirectory?

yes, they are there...