Update: The following problem has gone away by itself. It is possible that a reboot took care of it, and if so, that's just plain embarrassing... to me. That's like forgetting to wave a dead chicken over the keyboard... which I also didn't do, oops :)
Why does installing the Version 22.214.171.12401 EBF clear the previously-checked setting for ISQL - Tools - Options - Compatibility - Pressing the Esc key clears SQL statements and closes result sets?
This is displayed for both previously-existing and freshly-created databases, even though the checkbox was checked prior to the installation of 126.96.36.19901...
It also reset Options - SQL Anywhere - Results - Show results from each statement back to the default un-selected state:
This is a continuing problem... set and save the options, shut down and restart (database and dbisql), and all the options have been reset again... argh!